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Mayo Clinic researchers develop new antibody test to diagnose MS

ROCHESTER, Minn. — Mayo Clinic researchers have validated a new antibody test to diagnose multiple sclerosis (MS), a potentially disabling disease of the brain and spinal cord. Nearly 1 million people in the U.S. are affected by MS, according to the National Multiple Sclerosis Society. An antibody typically consists of two immunoglobulin heavy chains and two light chains. There are two types of light chains: kappa and lambda. The validated test measures kappa immunoglobulin free…

a futuristic 3D graphic image of a heart EKG, perhaps representing AI artificial intelligence

AI uses voice biomarkers to predict coronary artery disease

Imagine being able to record yourself reading and then having your clinician use those recordings to screen for various diseases, even from thousands of miles away. This technology may sound like science fiction, but Mayo Clinic researchers are using artificial intelligence (AI) to discover and test what the voice can reveal about a patient's heart health. In a recent study, the research team used an AI trained for specific vocal biomarkers to accurately predict which…

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The top 10 unanswered questions about medicines for people living with dementia

Timothy and Ann Pietsch pictured with Dr Emily Reeve. Up to 93 per cent of people living with dementia have experienced at least one medicine-related problem, leading to potentially harmful effects, but how do we improve these odds? A multi-step project including nationwide surveys and a workshop coordinated by the University of South Australia will today propose a solution – in the form of the...

Mayo Clinic medical personnel in full PPE tending to a patient with COVID-19 in a hospital bed

Breakthrough hospitalizations 'extremely uncommon' after COVID-19 immunity, Mayo study finds

ROCHESTER, Minn. — Fewer than 1 in 1,000 people who have been vaccinated or previously infected with COVID-19 were hospitalized with a new breakthrough infection, Mayo Clinic research finds. The study, which is published in Clinical Infectious Diseases, supports previous studies that show vaccination is the best way to prevent severe COVID-19 infection, hospitalization and death. "In the general primary care patient population, those who have been vaccinated have very low risk of subsequent hospitalization…

Male researcher pipetting genetic samples for testing

Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes

ROCHESTER, Minn. ― In a newly published study appearing in Genetics in Medicine, investigators from Mayo Clinic and Baylor College of Medicine found that targeted genomic information can play an important role in drug prescribing practices. The results from the "Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment" (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA…

Charlies rainbow

Rare genetic anomaly linked to 20% of childhood Acute Myeloid Leukemia cases

Little Charlie, who  died of AML at just age three. It’s a diagnosis you never want to hear: Acute Myeloid Leukaemia (AML). These three words represent a devastating diagnosis of childhood cancer with dire consequences for many families. In Australia AML is the most common form of acute leukemia in adults and is responsible for one fifth of all childhood leukemia cases (about 50 children ) each...