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Research News Chinese Academy of Sciences

CIP2A Found to Link DNA Repair and Tumor Sensitivity to Radiotherapy

DNA double-strand breaks (DSBs) are posing serious threats to genome stability. During mitosis, cells mainly rely on polymerase theta (Polθ) -mediated repair to fix these breaks. However, how the CIP2A-TOPBP1 complex regulates this process remains unclear. In a study published in PNAS , a team led by Prof. ZHAO Guoping from the Hefei Institutes of Physical Science of the Chinese Academy of Science

Medical Research Life Sciences Proteins #Chinese Academy of Sciences #Research News #Proteins #medical research #clinical research #genomics #biology
Research News Chinese Academy of Sciences

Researchers Reveal Origins of De Novo Coronary Collateral Formation in Cardiac Repair

In a study published in Science , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. LIU Kathy O. from The Chinese University of Hong Kong, developed a series of genetic lineage-tracing tools to investigate the origins of newly formed coronary collateral art

Medical Research Life Sciences Health #Chinese Academy of Sciences #Research News #Health #medical research #clinical research #genomics #biology
Research News Chinese Academy of Sciences

Lymphatic Vessels Invade Bone in Disease but Absent in Health and Regeneration

In a study published in Cell , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. Ralf H. Adams from the Max Planck Institute for Molecular Biomedicine, Germany, reported the absence of lymphatic vessels in homeostasis and regenerating bone and their abnorma

Medical Research Life Sciences Health #Chinese Academy of Sciences #Research News #Health #medical research #clinical research #genomics #biology
Research News Adelaide University

New funding backs pioneering research to make brain cancer treatment more effective

Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumours, while reducing damage to healthy tissue.

Research Medical Research Life Sciences #Adelaide University #Adelaide #medical research #clinical research #genomics #biology
Research News U.S. National Science Foundation

NSF launches three new Science and Technology Centers with $90M investment in transformative research

The U.S. National Science Foundation is investing $90 million over five years to support three new NSF Science and Technology Centers (NSF STC). These centers will advance American leadership in…

Fusion Energy Medical Research Life Sciences #U.S. National Science Foundation #fusion #plasma physics #medical research #clinical research #genomics #biology
Research News University at Buffalo

Sex differences in radiation side effects

UB researchers are exploring why female head and neck cancer patients tend to get the worst of it.

Research Medical Research Life Sciences #University at Buffalo #UBNow #research #medical research #clinical research #genomics #biology
Research News University of California, Riverside

NIH grant will advance study of the primary cilium

Five-year award will investigate how the tiny cellular structure shapes protein production, energy use, and brain development

Medical Research Life Sciences Environment & Climate #University of California, Riverside #Health #Social Science / Education #medical research #clinical research #genomics #biology #climate
Research News Tohoku University

AI Helps Identify Regulatory Hub for Aging in Hematopoietic Stem Cells

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell. Throughout life, they can produce new blood cells to replace those lost because of infection, bleeding, or chemotherapy. However, as people and animals age, hematopoietic stem cells become less effective.

Medical Research Life Sciences #Tohoku University #Research Releases #medical research #clinical research #genomics #biology
Research News Yale University

Can you slow the aging process? Study reveals which interventions might help

When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.

Research Medical Research Life Sciences #Yale University #research #Yale #Yale News #medical research #clinical research #genomics #biology
Research News Yale University

Beyond GLP-1s: Combination Therapy, New Hormones Reshape Obesity Treatment

The first wave of blockbuster obesity medications, including semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro), transformed weight loss by achieving levels once thought possible only with bariatric surgery.

Research Medical Research Life Sciences #Yale University #research #Yale #Yale News #medical research #clinical research #genomics #biology
Research News Adelaide University

Scientists identify molecule driving one of the deadliest forms of breast cancer

Australian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.

Research Medical Research Life Sciences #Adelaide University #Adelaide #medical research #clinical research #genomics #biology
Features Brookhaven National Laboratory

Built for Discovery: LBMS at Five Years

LBMS marks five years as a leading cryo-EM facility, advancing biological discovery through cutting-edge imaging and collaboration.

Medical Research Life Sciences Environment & Climate #Brookhaven National Laboratory #medical research #clinical research #genomics #biology #climate #decarbonization
Features Brookhaven National Laboratory

Targeting Antibiotic Resistance

Researchers uncover a critical molecular switch that helps bacteria survive environmental stress and antibiotic exposure.

Medical Research Life Sciences Environment & Climate #Brookhaven National Laboratory #medical research #clinical research #genomics #biology #climate #decarbonization
Research News University of Minnesota Medical School

From Seed Funding to Breakthroughs: CCRF Visits the Center for Genome Engineering

Early Investment in an Emerging Scientist The Children’s Cancer Research Fund (CCRF) recently visited the Center for Genome Engineering at the University of Minnesota.

Medical Research Life Sciences Research #University of Minnesota Medical School #UMN Medical School #CGE #research #TIL #medical research #clinical research #genomics
Research News Lawrence Berkeley National Laboratory

Planning a New Era of Discovery with the Upgraded Advanced Light Source

Scientists around the world use the focused beams of light generated by the Advanced Light Source (ALS) synchrotron to study molecules and materials with…

ALS-U Particle Physics Medical Research #Lawrence Berkeley National Laboratory #ALS-U #Particle Physics #High Energy Physics #medical research #clinical research #genomics #biology
Research News Chinese Academy of Sciences

Researchers Reveal How Gatekeeper Enzyme UGCG Controls Glycosphingolipid Synthesis

Glycosphingolipids (GSLs) are sugar-containing membrane lipids that help organize cell surfaces and regulate signaling, immune recognition, differentiation and neuronal function. Human cells produce several hundred GSL species through stepwise modification of their sugar groups, and this diversity begins with a single committed reaction, in which uridine diphosphate glucose (UDP-glucose) ceramide

Medical Research Health #Chinese Academy of Sciences #Research News #Health #medical research #clinical research
Research News Chinese Academy of Sciences

Researchers Reveal How Auxin Establishes Pistil Boundary by Degrading Key Transcription Factor

Have you ever wondered how a flower ensures that it's pollen-catching "landing pad" (the stigma) stays neatly separated from the "pollen tube highway" beneath it (the style)? This clear boundary is crucial for plant reproduction, but for decades, biologists didn't know how it was drawn. In a study published in PNAS , researcher s from the Institute of Botany of the Chinese Academy of Sciences (CAS

Life Sciences Evolution #Chinese Academy of Sciences #Research News #Evolution #genomics #biology
Research News Chinese Academy of Sciences

Scientists Unlock "Ancestral Code" of Banana Family

Scientists have recently reconstructed the ancestral karyotype of the banana family, revealing how chromosome numbers decreased stepwise from 17 to 9 - 11 over evolutionary time. The study was led by scientists from the South China Botanical Garden (SCBG) of the Chinese Academy of Sciences (CAS), in collaboration with researchers from Sichuan University and other institutions . The findings were p

Fusion Energy Life Sciences Biodiversity #Chinese Academy of Sciences #Research News #biodiversity #paleontology #fusion #plasma physics #genomics #biology
Research News Chinese Academy of Sciences

Study Reveals Resistance Mechanism of Wild Apple Against Valsa Canker

Scientists have recently revealed the molecular mechanism of the MsWRKY65– MsLNC1 –MsTRX5 module conferring resistance to Valsa canker in wild apple. Led by Prof. Z HANG Daoyuan from the Xinjiang Institute of Ecology and Geography (XIEG) of the Chinese Academy of Sciences (CAS), the study was published in Horticulture Research . Apple Valsa canker, caused by the necrotrophic fungus Valsa mali , le

Medical Research Biodiversity #Chinese Academy of Sciences #Research News #biodiversity #medical research #clinical research
Research News Chinese Academy of Sciences

Study Reveals How Spruce Species Maintain Their Identity Despite Hybridization

In a study published in BMC Biology , researchers from the Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences and Lanzhou University revealed a sophisticated natural selection process that protects closely related spruce trees from the genetic chaos of interbreeding. These findings provide new evidence for taxonomic delimitation , helping scientists distinguish speci

Life Sciences Bioengineering #Chinese Academy of Sciences #Research News #Bioengineering #genomics #biology
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