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Fighting pathogens by watching how they read their own DNA

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New funding backs pioneering research to make brain cancer treatment more effective

Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumours, while reducing damage to healthy tissue.

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NSF launches three new Science and Technology Centers with $90M investment in transformative research

The U.S. National Science Foundation is investing $90 million over five years to support three new NSF Science and Technology Centers (NSF STC). These centers will advance American leadership in…

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Researchers Develop Bridge RNA-guided Large-fragment Editing System for Cross-kingdom Precise Genome Manipulation

Precise manipulation of large genomic fragments is a critical need in crop breeding and synthetic biology. In crop genomes, superior traits are often associated with structural variations. However, existing large-fragment editing tools such as CRISPR-Cas systems and site-specific recombinases have limitations. In 2024, the development of the bridge RNA-guided IS110-family recombinase system provid

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CIP2A Found to Link DNA Repair and Tumor Sensitivity to Radiotherapy

DNA double-strand breaks (DSBs) are posing serious threats to genome stability. During mitosis, cells mainly rely on polymerase theta (Polθ) -mediated repair to fix these breaks. However, how the CIP2A-TOPBP1 complex regulates this process remains unclear. In a study published in PNAS , a team led by Prof. ZHAO Guoping from the Hefei Institutes of Physical Science of the Chinese Academy of Science

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Features Brookhaven National Laboratory

Built for Discovery: LBMS at Five Years

LBMS marks five years as a leading cryo-EM facility, advancing biological discovery through cutting-edge imaging and collaboration.

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Targeting Antibiotic Resistance

Researchers uncover a critical molecular switch that helps bacteria survive environmental stress and antibiotic exposure.

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Research News University of Minnesota Medical School

From Seed Funding to Breakthroughs: CCRF Visits the Center for Genome Engineering

Early Investment in an Emerging Scientist The Children’s Cancer Research Fund (CCRF) recently visited the Center for Genome Engineering at the University of Minnesota.

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