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<p>Infection of the lungs by pathogens like SARS-CoV-2 causes inflammation, which can turn deadly. Azeliragon reduces inflammation by blocking the activity of a protein called RAGE, and could be used to treat multiple lung diseases, including COVID-19. Credit: Shutterstock</p>

Cantex licenses intellectual property from Harvard University to develop repurposed drug identified by Wyss Institute to treat inflammatory lung diseases including COVID-19

By Lindsay Brownell (BOSTON, MA and WESTON, FL) – Cantex Pharmaceuticals, Inc., a clinical-stage pharmaceutical company based in Weston, FL, and the Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that Cantex has secured a global license from Harvard University’s Office of Technology Development (OTD) to develop azeliragon, a small-molecule drug in clinical…

<p>Jennifer Lewis’ and Ryuji Morizane’s teams found previously that culturing kidney organoids under fluid flow causes endogenous endothelial progenitors to create more mature vascular networks which pervade the whole organoid and interact with epithelial compartments. This finding presents a critical advance toward the future development of new approaches by Trestle to treat chronic kidney disease using 3D bioprinting and stem cell-based tissue engineering. Credit: Wyss Institute at Harvard University</p>

Harvard University licenses kidney engineering technology to Trestle Biotherapeutics to facilitate new kidney replacement therapies

By Benjamin Boettner (BOSTON/CAMBRIDGE, Mass.) — A newly launched startup is building upon innovations developed over several years at the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering & Applied Sciences (SEAS), and Brigham and Women’s Hospital (Brigham) to engineer functional kidney tissue for renal repair and…

<p>Jennifer Lewis’ and Ryuji Morizane’s teams found previously that culturing kidney organoids under fluid flow causes endogenous endothelial progenitors to create more mature vascular networks which pervade the whole organoid and interact with epithelial compartments. This finding presents a critical advance toward the future development of new approaches by Trestle to treat chronic kidney disease using 3D bioprinting and stem cell-based tissue engineering. Credit: Wyss Institute at Harvard University</p>

Harvard University licenses kidney engineering technology to Trestle Biotherapeutics to facilitate new kidney replacement therapies

By Benjamin Boettner (BOSTON/CAMBRIDGE, Mass.) — A newly launched startup is building upon innovations developed over several years at the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering & Applied Sciences (SEAS), and Brigham and Women’s Hospital (Brigham) to engineer functional kidney tissue for renal repair and…

Scientists from LanzaTech, Northwestern University and Oak Ridge National Laboratory engineered a microbe, shown in light blue, to convert molecules of industrial waste gases, such as carbon dioxide and carbon monoxide, into acetone. The same microbe can also make isopropanol. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Carbon-negative platform turns waste gases into valuable chemicals

Carbon-negative platform turns waste gases into valuable chemicals

pearcejw@ornl.gov Mon, 02/21/2022 - 13:00

A team of scientists from LanzaTech, Northwestern University and ORNL have developed carbon capture technology that harnesses emissions from industrial processes to produce acetone and isopropanol

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Summit study spins up new insights into correlated electron systems

Summit study spins up new insights into correlated electron systems

pearcejw@ornl.gov Fri, 02/18/2022 - 10:37

A study led by researchers at ORNL used the nation’s fastest supercomputer to close in on the answer to a central question of modern physics that could help conduct development of the next generation of energy technologies.

This computer-generated image of the JET tokamak shows what one would see if its walls were transparent, revealing the plasma inside. Credit: UK Atomic Energy Authority

ORNL experts help measure new world record for fusion energy

ORNL experts help measure new world record for fusion energy

pearcejw@ornl.gov Thu, 02/17/2022 - 12:52

A new fusion record was announced February 9 in the United Kingdom: At the Joint European Torus, or JET, the team documented the generation of 59 megajoules of sustained fusion energy, more than doubling the

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Nurse Doris Scott surmounted barriers during ORNL’s early years

Nurse Doris Scott surmounted barriers during ORNL’s early years

pearcejw@ornl.gov Thu, 02/17/2022 - 11:44

When in 1948 Doris Belle Scott, just graduated from Meharry Medical College School of Nursing, sat for her interview for a position at Oak Ridge National Laboratory, the medical director, J.S. Felton, explained the Laboratory's philosophy of industrial health