When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.
The first wave of blockbuster obesity medications, including semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro), transformed weight loss by achieving levels once thought possible only with bariatric surgery.
Using a new combination of computational tools to analyze ancient DNA , Yale researchers have discovered two ancient, extinct giant tortoise lineages that once lived on the Galapagos Islands.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney failure. Despite decades of research, treatment options for the disease remain limited, and many patients ultimately require dialysis or kidney transplantation.
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Medicine is learned not only in lecture halls and hospital wards, but also in the everyday conversations and interactions where clinicians build lasting relationships with patients over time. For Cynthia McNamara, MD , associate professor of medicine (general medicine) at Yale School of Medicine and a physician at VA Connecticut, those spaces have shaped her approach to ambulatory education, mento
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Two disorders with big names—trichotillomania (repeated hair-pulling) and excoriation disorder (repeated skin-picking)—were the focus of a recent Yale study looking at potential genetic causes. The two disorders are part of a group called body-focused repetitive behaviors, or BFRBs.
Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumours, while reducing damage to healthy tissue.
Early Investment in an Emerging Scientist The Children’s Cancer Research Fund (CCRF) recently visited the Center for Genome Engineering at the University of Minnesota.
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Australian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.
The U.S. National Science Foundation is investing $90 million over five years to support three new NSF Science and Technology Centers (NSF STC). These centers will advance American leadership in…
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DNA double-strand breaks (DSBs) are posing serious threats to genome stability. During mitosis, cells mainly rely on polymerase theta (Polθ) -mediated repair to fix these breaks. However, how the CIP2A-TOPBP1 complex regulates this process remains unclear. In a study published in PNAS , a team led by Prof. ZHAO Guoping from the Hefei Institutes of Physical Science of the Chinese Academy of Science
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In a study published in Science , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. LIU Kathy O. from The Chinese University of Hong Kong, developed a series of genetic lineage-tracing tools to investigate the origins of newly formed coronary collateral art
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Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell. Throughout life, they can produce new blood cells to replace those lost because of infection, bleeding, or chemotherapy. However, as people and animals age, hematopoietic stem cells become less effective.
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In a study published in Cell , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. Ralf H. Adams from the Max Planck Institute for Molecular Biomedicine, Germany, reported the absence of lymphatic vessels in homeostasis and regenerating bone and their abnorma
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LBMS marks five years as a leading cryo-EM facility, advancing biological discovery through cutting-edge imaging and collaboration.
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Researchers uncover a critical molecular switch that helps bacteria survive environmental stress and antibiotic exposure.
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Scientists around the world use the focused beams of light generated by the Advanced Light Source (ALS) synchrotron to study molecules and materials with…
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