In collaboration with Professor Shinse Yamaga and Professor Chisa Shukuminami of the Department of Biomolecular Functions, Graduate School of Medical Sciences, Hiroshima University, and Professor Kenta Sumiyama of the Graduate School of Bioagricultural Sciences, Nagoya University, Assistant Professor Hitomi Watanabe, Professor Gen Kondo of the Institute of Medical Biology, Kyoto University, and others, they identified an enhancer (*2) that controls the expression of the transcription factor Scx (*1), which is essential for the maturation of tendons and ligaments, and clarified its role. Our research group first analyzed the activity of candidate genomic regions using lacZ Tg mouse (*3) embryos and revealed that a 5.3kb genomic region that includes part of the mouse Scx gene and its downstream region has enhancer activity. Furthermore, we found that the evolutionarily highly conserved region (CSE) contained in this 5.3kb region also has enhancer activity. Next, when we created and analyzed mice lacking CSE using genome editing technology, we found that Scx expression was significantly reduced during the limb formation process. Also, usually
Medical Research#Hiroshima University#medical research#clinical research
Upgraded facilities designed to promote research innovation, collaboration
Research NewsMedical ResearchEnvironment & Climate#Ohio State University#Campus#staff#Share on: X#More Ohio State News#View all headlines - More Ohio State News#medical research#clinical research
Daniel Lee has been awarded a $750,000 Tauopathy Challenge Workshop grant supported by the Rainwater Charitable Foundation, the Alzheimer’s Association, the Aging Mind Foundation and CurePSP.
Medical ResearchLife Sciences#University of Kentucky#medical research#clinical research#genomics#biology
The long-term future of the South Australian Health and Medical Research Institute has been secured with a landmark agreement that will bolster South Australia's global health and medical research capabilities.
ResearchMedical Research#Adelaide University#Adelaide#medical research#clinical research
Dr. Sam Ward is currently transitioning away from his role as vice dean for research in the School of Medicine and is a professor in the Departments of Orthopaedic Surgery and Radiology in the School of Medicine and Bioengineering in the Jacobs School of Engineering.
ResearchMedical Research#University of California San Diego#UC San Diego#UCSD Today#medical research#clinical research
Research NewsUniversity of Minnesota Medical School
Celebrating two decades of impact, the University of Minnesota’s Program in Health Disparities Research (PHDR) transformed community-engaged research from an overlooked initiative into a mainstream academic standard, redefining institutional excellence, trust, and research funding along the way.
Medical ResearchResearch#University of Minnesota Medical School#UMN Medical School#PHDR#Community Engagement#research#medical research#clinical research
Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumours, while reducing damage to healthy tissue.
The center was established in 2021 as a developmental center in partnership with UTHealth Houston, Baylor College of Medicine, and the Texas Biomedical Research Institute.
Medical Research#UTHealth Houston#research#Top News#medical research#clinical research
Normal hormonal changes create conditions allowing virus to thrive
Research NewsMedical ResearchEnvironment & Climate#Ohio State University#medical#Science#Share on: X#More Ohio State News#View all headlines - More Ohio State News#medical research#clinical research
The U.S. National Science Foundation is investing $90 million over five years to support three new NSF Science and Technology Centers (NSF STC). These centers will advance American leadership in…
Fusion EnergyMedical ResearchLife Sciences#U.S. National Science Foundation#fusion#plasma physics#medical research#clinical research#genomics#biology
Glycosphingolipids (GSLs) are sugar-containing membrane lipids that help organize cell surfaces and regulate signaling, immune recognition, differentiation and neuronal function. Human cells produce several hundred GSL species through stepwise modification of their sugar groups, and this diversity begins with a single committed reaction, in which uridine diphosphate glucose (UDP-glucose) ceramide
Medical ResearchHealth#Chinese Academy of Sciences#Research News#Health#medical research#clinical research
Annette Mosman RA, MSc, has been appointed by the Minister of Education, Culture and Science as a member of the Supervisory Board of the UvA, effective 26 August. The appointment is for a period of four years. She succeeds Mohcine Ouass, whose term expires on the same day.
Medical Research#University of Amsterdam#medical research#clinical research
Obesity and eating disorders have traditionally been treated as separate areas of healthcare – but the rapid rise of GLP-1 medicines is increasingly bringing the two together.
ResearchMedical Research#Adelaide University#Adelaide#medical research#clinical research
Researchers affiliated with UTHealth Houston, competing under the team name Novamab AI, placed among the top five teams in the international AIntibody Challenge, a blinded, prospective benchmark published in Nature Biotechnology .
Medical Research#UTHealth Houston#research#medical research#clinical research
