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<p>John Chaput in lab. Steve Zylius / UCI</p>

Pharmacutical Science

X Marks the Spot

Three questions with professor of pharmaceutical sciences John Chaput, who discusses using synthetic genetics in drug discovery

Pharmacutical Science

Pharmacists play key role in treating seniors with opioid use disorder, UCI professor writes

<p>This graphic illustrates how the C6 peptide blocks Hv1 channels in the white blood cells called neutrophils, suppressing uncontrolled inflammation and fluid buildup seen in severely damaged lungs.</p>

Pharmacutical Science

UC Irvine, UCLA researchers identify new therapeutic approach to prevent ARDS

Designed peptide blocks top cause of life-threatening lung damage with pneumonia

Pharmacutical Science

The art of collaborative healthcare

Innovative health sciences curriculum prepare students for real-world settings

Pharmacutical Science

2022 Year in Review – UCI Health

A year of groundbreaking growth and accomplishments

Pharmacutical Science

2022 Year in Review – UCI in the community

A year of groundbreaking growth and accomplishments

<p>Sammy Alhassen, Wedad Alhassen, Amal Alachkar, Kiki Jiaqi Chen and Roudabeh Vakil Monfared (from left) of UCI’s Department of Pharmaceutical Sciences found that removal of cilia from the brain’s striatum region in mice caused a unique set of behaviors that share a characteristic found in mental and neurological disorders ranging from schizophrenia to Huntington’s disease: impaired time perception and judgment. Lamees Alhassen / UCI</p>

Pharmacutical Science

UCI researchers discover crucial role of brain’s striatum cilia in time perception

Results reveal possible new therapeutic targets for mental and neurological disorders

<p>“Our study established that cognitive toxicity is a neurological complication that can appear at the time of cancer diagnosis in adolescents and young adults before treatment begins. We strongly recommend that clinicians closely monitor AYA cancer patients’ cognitive performance to help prevent further deterioration,” says Alexandre Chan, corresponding author and UCI chair and professor of clinical pharmacy practice. Christopher Todd / Christopher Todd Studios</p>

Pharmacutical Science

UCI-led study discovers pre-treatment cognitive impairment in younger cancer patients

Toxicity must be evaluated and managed at diagnosis to help prevent further deterioration

<p>“Policy efforts to reduce the gaps in opioid addiction treatment have largely ignored the role of restrictive regulations that reduce availability in community pharmacies. Our paper addresses these barriers and makes recommendations to improve and expand access,” says co-author Jonathan Watanabe, UCI professor of clinical pharmacy practice. Steve Zylius / UCI</p>

Pharmacutical Science

Paper co-authored by UCI professor addresses access to medication for opioid use disorder

<p>Pierre Baldi, UCI Distinguished Professor of computer science, and Amal Alachkar, neuroscientist and professor of teaching in UCI’s Department of Pharmaceutical Sciences, conducted a thorough examination of peer-reviewed literature on the most prevalent mental health disorders and found that circadian rhythm disruption is present in nearly all of them. They recommend exploring the molecular foundations of the linkage. UCI</p>

Pharmacutical Science

Circadian rhythm disruption found to be common among mental health disorders

UCI researchers spotlight links and propose investigation into molecular underpinnings

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