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Patients with mitral annulus calcification at higher risk of heart valve and cardiovascular disease, Mayo Clinic research finds

ROCHESTER, Minn. — A retrospective review of more than 24,000 patients who underwent an echocardiogram at Mayo Clinic finds that nearly one-quarter of the patients had mitral annulus calcification, a chronic degeneration of tissue at the base of the heart's mitral valve. Mitral valve dysfunction was more than twice as prevalent for those patients, who also were at higher risk of all-cause mortality. Mitral annulus calcification has been associated with cardiovascular diseases and events, as…