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Identifying the Underlying Causes of Ovarian Cancer

Pandemic prep needs ‘smart surveillance’ to predict viral spillovers

“Smart surveillance” for viral spillover from animals to humans, targeted preparedness and drug and vaccine research, and worldwide cooperation on surveillance and stopping disease spread are required to reduce deaths and lessen the economic consequences of the next pandemic, according to an international team of scientists.

Medical Science

Scientists hit their creative peak early in their careers

A new study provides the best evidence to date that scientists overall are most innovative and creative early in their careers.

Medical Science

A potential target for developing broad-spectrum antiviral therapies

Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

Using deep Hi-C sequencing, a tool used for studying 3D genome organization, the researchers created a high-resolution map of retinal cell chromatin contract points, shown left. The entire map included about 704 million contact points. Shown right, more than 60,000 chromatin loops are represented on a portion of the map.

Medical Science

3D map reveals DNA organization within human retina cells

NIH scientists shed light on how genetic architecture determines gene expression, tissue-specific function, and disease phenotype in blinding diseases.

Medical Science

Research provides critical information about the size and growth speed of gliomas

An important new clue for preventing and treating brain tumors known as gliomas has been identified in research led by the Lunenfeld-Tannenbaum Research Institute (LTRI) at Mount Sinai Hospital in Toronto and Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine. The study, published in the journal Science, provides a rare window into the biological changes behind glioma development.