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<p>Mice raised in built environments with different relative abundances of diverse microbes (left and right) have a correspondingly diverse gut microbiome. These signature characteristics remained even when the mice were moved to a new facility, and they persisted into the next generation. (Credit: Zosia Rostomian/Berkeley Lab)</p>

Genes, Early Environment Sculpt the Gut Microbiome

Scientists from Berkeley Lab and PNNL have found that genes and early environment play big roles in shaping the gut microbiome. The microbes retained a clear “signature” formed where the mice were first raised, and the characteristics carried over to the next generation. The findings could potentially be used to develop designer diets optimized to an individual’s microbiome.