When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.
The first wave of blockbuster obesity medications, including semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro), transformed weight loss by achieving levels once thought possible only with bariatric surgery.
Daniel Lee has been awarded a $750,000 Tauopathy Challenge Workshop grant supported by the Rainwater Charitable Foundation, the Alzheimer’s Association, the Aging Mind Foundation and CurePSP.
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Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumours, while reducing damage to healthy tissue.
The U.S. National Science Foundation is investing $90 million over five years to support three new NSF Science and Technology Centers (NSF STC). These centers will advance American leadership in…
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LBMS marks five years as a leading cryo-EM facility, advancing biological discovery through cutting-edge imaging and collaboration.
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Researchers uncover a critical molecular switch that helps bacteria survive environmental stress and antibiotic exposure.
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Precise manipulation of large genomic fragments is a critical need in crop breeding and synthetic biology. In crop genomes, superior traits are often associated with structural variations. However, existing large-fragment editing tools such as CRISPR-Cas systems and site-specific recombinases have limitations. In 2024, the development of the bridge RNA-guided IS110-family recombinase system provid
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DNA double-strand breaks (DSBs) are posing serious threats to genome stability. During mitosis, cells mainly rely on polymerase theta (Polθ) -mediated repair to fix these breaks. However, how the CIP2A-TOPBP1 complex regulates this process remains unclear. In a study published in PNAS , a team led by Prof. ZHAO Guoping from the Hefei Institutes of Physical Science of the Chinese Academy of Science
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Early Investment in an Emerging Scientist The Children’s Cancer Research Fund (CCRF) recently visited the Center for Genome Engineering at the University of Minnesota.
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In a study published in Science , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. LIU Kathy O. from The Chinese University of Hong Kong, developed a series of genetic lineage-tracing tools to investigate the origins of newly formed coronary collateral art
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Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell. Throughout life, they can produce new blood cells to replace those lost because of infection, bleeding, or chemotherapy. However, as people and animals age, hematopoietic stem cells become less effective.
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In a study published in Cell , a team led by Prof. ZHOU Bin from the Center for Excellence in Molecular Cell Science (Shanghai Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, along with Prof. Ralf H. Adams from the Max Planck Institute for Molecular Biomedicine, Germany, reported the absence of lymphatic vessels in homeostasis and regenerating bone and their abnorma
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Australian researchers have uncovered a promising new way to tackle one of the most aggressive forms of breast cancer, raising hopes for more effective treatments to stop the disease from spreading.
Researchers identified a previously overlooked pattern of DNA mutations in colorectal cancer. The pattern had been detected in large cancer-genome datasets before, but researchers had interpreted it as a combination of other, already known mutation patterns.
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