The human body is a marvel of remake and renewal. We regularly replace some of our estimated 37 trillion cells – about 300 billion or 1 percent of our cells each day - with healthy substitutes. We remove damaged or aging, senescent cells and cellular debris from our organs and tissues every second of the day. How important is it that cellular waste be properly removed?
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Researchers at the Swammerdam Institute for Life Sciences (SILS) of the Faculty of Science have uncovered how mammary-gland cells decide when to activate Wnt4, a gene with a central role in mammary-gland development. Their findings reveal how distant stretches of non-coding DNA work together in three dimensions to control gene activity.
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A mule has helped researchers build the most complete reference genomes to date for horses and donkeys, giving scientists access to complex regions of DNA that earlier versions could not fully capture.
Medical ResearchLife Sciences#University of Kentucky#medical research#clinical research#genomics#biology
Researchers at UC San Diego have demonstrated that one of biology’s most essential enzymes can accurately read and transcribe an expanded genetic alphabet containing eight DNA letters instead of the four used by all known life.
ResearchMedical ResearchLife Sciences#University of California San Diego#UC San Diego#UCSD Today#medical research#clinical research#genomics#biology
As it tries to defend itself from stroke, the brain can paradoxically trigger the formation of tiny new clots in minor blood vessels, damaging tissue even after the original culprit has been removed, new research shows. The findings help explain why nearly half of treated stroke patients don’t recover — and identify potential new treatments.
Medical ResearchLife Sciences#University of Colorado Boulder#CU Boulder#CU Boulder Today#medical research#clinical research#genomics#biology
