A research group led by Professor Hideki Ohdan of the Department of Gastrointestinal and Transplant Surgery at Hiroshima University Graduate School of Medical Sciences, Dr. Yukitoshi Shidawara, and Dr. Kentaro Ide of Hiroshima Prefectural Hospital investigated the risk of production of de novo donor-specific antibodies (dnDSA), which newly appear after kidney transplantation, in 210 patients who underwent kidney transplantation at Hiroshima University Hospital. dnDSA causes antibody-related rejection and affects long-term survival of transplanted kidneys. In addition to HLA molecular mismatch analysis, which is widely used worldwide, the research group focused on patient genetic variations (single nucleotide polymorphisms (SNPs), which are widely present in the general population), and analyzed genes related to follicular helper T cells (Tfh cells), which assist in antibody production. As a result, we found that not only the HLA compatibility between donor and patient, but also the genetic background related to Tfh cells of the patient caused dnDSA production.
An international joint research group consisting of Associate Professor Takayuki Ishii of the Okayama University Graduate School of Advanced Research (Planetary Materials Research Institute), Specially Appointed Assistant Professor Jun Takaichi of Hiroshima University, Ehime University, Teikyo University of Science, Kyoto University, High Brightness Photon Science Research Center, and the Beijing High Pressure Research Center in China is working on a Kawai-type multi-anvil high-pressure generator 2) at the large synchrotron radiation facility SPring-8 1). Using a combination of synchrotron radiation and X-rays, we precisely measured the water-containing volume of Dave Maoite, a major mineral in the Earth's lower mantle, at high temperatures and pressures up to the conditions at the top of the lower mantle. This result was published in the British geoscience journal Communications Earth & Environment on July 24th. The water content of Dave Maoite is difficult to determine experimentally, which has been a major barrier to building deep Earth water cycle models. From the results of this experiment, the volumes of Dave Maoite synthesized under dry and hydrated conditions are almost the same, and the water solubility is lower than the conventional estimate.
Hiroshima University Graduate School of Medical Sciences, Department of Public Health (Associate Professor Masaru Tahara), in collaboration with Waseda University (Professor Emeritus Shigenobu Shibata) and Combi Co., Ltd. Life Science Division (Headquarters: Taito-ku, Tokyo; President and CEO: Yasuji Matsuura), conducted a study aimed at clarifying the relationship between postpartum mental health and regularity of mealtimes among women in Japan who have their first child between 0 and 12 months old. The results of this study revealed that people with regular mealtimes had significantly lower scores on the Edinburgh Postnatal Depression Questionnaire (EPDS) (*1), an indicator of postnatal depression symptoms, than those with irregular meal times. On the other hand, no significant relationship was found between breakfast intake frequency and EPDS score. This study shows that not only the content of meals, but also the perspective of ``when to eat'' may be important when considering postpartum mental health. (*1) EPDS: The higher the score, the stronger the depressive symptoms.
A research group including Assistant Professor Sylvia Natsuko Akutsu, Graduate Student Risa Matsumura, Associate Professor Takamoto Asano, Emeritus Professor Shinya Matsuura, Professor Megumi Sasaya, Professor Shinji Yoshinaga of the Atomic Bomb Radiological Research Institute of Hiroshima University, and Professor Tatsuo Miyamoto of the Yamaguchi University Graduate School of Medicine is using genome editing (*2) to develop ataxia-telangiectasia-like disorder (AT-like disorder). We created a model mouse with a mutation in the MRE11 gene found in patients with ATLD (*3). When we examined this mouse model, we found that when it was exposed to radiation under certain genetic conditions, the number of tumors that formed in the small intestine increased significantly. The results of this research were published in the online version of the British scientific journal Scientific Reports on August 14, 2026.
For its review of the Bail Act 1985 (SA), the South Australian Law Reform Institute (SALRI) is now commencing its community engagement, including visits to towns in regional South Australia, to seek input from interested parties and individuals.
A new National Bureau of Economic Research from the University of California San Diego shows that wildfire damage can have long-term economic consequences for households, resulting in income losses, relocation of residents as well as slow rebuilding for several years after a fire.
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UC San Diego's Qualcomm Institute hosted three summer internships in semiconductors, game design and AI, giving students hands-on, workforce-ready skills.
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A new study led by researchers at the University of California San Diego shows that the brain does not simply respond to breathing as a steady rhythm. Instead, the detailed shape of each individual breath is closely linked to the shape of neural activity in brain regions.
Research#University of California San Diego#UC San Diego#UCSD Today
The University of California San Diego has received a grant of more than $1 million from the Ewing Marion Kauffman Foundation to support a national research project examining how entrepreneurs access financing during the earliest stages of the small business lending process.
Research#University of California San Diego#UC San Diego#UCSD Today
A research team at UC San Diego’s Scripps Institution of Oceanography found a way to distinguish the magnetism that clay materials acquire over time from the magnetism those materials acquired the day they were made, giving museums everywhere a chance to detect fake artifacts.
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A new study suggests this twist arises from how the rapidly growing spine develops around the gut, offering fresh insight into one of nature’s most unusual body plans.
Life SciencesResearch#University of British Columbia#UBC News#News Tips#Science & Technology#Department of Zoology#Discover and Innovate for Impact#Faculty of Dentistry#Faculty of Science
AUG 31, 2026 | Julie Jansen From left: UAH mascot Charger Blue; Brian Niswonger, a senior majoring in kinesiology; Joshua Kolby a 2026 aerospace engineering graduate; UAH President Dr. Don Leo, UAH President; and Dr. Dave Puleo, provost and executive vice president for academic affairs. Michael Mercier | UAH Brian Niswonger, a senior majoring in kinesiology, was named the AACE Intern of the Year, while Joshua Kolby, a 2026 aerospace engineering graduate, was named AACE Co-op of the Year. The stu
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